Zu "102271-49-8" wurden 2 Artikel gefunden!
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PGS-IN-1
Artikelnummer: TGM-T10098-100mg
Description: PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 µM) and 5-lipoxygenase (IC50: 1.05 µM). Target: Prostaglandin Receptor, Lipoxygenase. Smiles: CC(C)(C)c1cc(\C=C2/CCOC2=O)cc(c1O)C(C)(C)C. References: Katsumi I, et al. Studies on styrene derivatives. I. Synthesis and...
| Schlagworte: | KME-4 |
| CAS | 102271-49-8 |
| MW: | 302.41 D |
ab 42,00 €
PGS-IN-1
Artikelnummer: Cay37666-1
PGS-IN-1 is a non-steroidal anti-inflammatory drug (NSAID) and a dual inhibitor of COX and 5-lipoxygenase (5-LO, IC50s = 0.44 and 0.85 µM, respectively). It is selective for 5-LO over 12-LO (IC50 = >100 µM for the rabbit enzyme ). Oral administration of PGS-IN-1 (10 mg/kg per day) inhibits paw swelling and bone...
| Schlagworte: | KME-4, PG Synthetase Inhibitor 1, PGS Inhibitor 1, Prostaglandin Synthetase Inhibitor 1,... |
| Anwendung: | NSAID, COX / 5-LO dual inhibitor |
| CAS | 102271-49-8 |
| MW: | 302.4 D |
ab 40,00 €
