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S0859
Artikelnummer: Cay18497-1
S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH, particularly in myocytes. It inhibits intracellular pH recovery in myocytes with a Ki value of 1.7 µM, with full inhibition occurring at ~30 µM. S0859 does not affect other...
| Schlagworte: | 2-chloro-N-[[2'-[(cyanoamino)sulfonyl][1,1'-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide |
| Anwendung: | SLC4A7 blocker |
| CAS | 1019331-10-2 |
| MW: | 530 D |
ab 51,00 €
S0859
Artikelnummer: TGM-T2010-100mg
Description: S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH. Target: Others. Smiles: Cc1ccc(CN(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC#N)C(=O)c2ccccc2Cl)cc1. References: Larsen AM, et al. ChemMedChem. 2012 Oct,7(10):1808-14.
| CAS | 1019331-10-2 |
| MW: | 530.04 D |
ab 32,00 €
