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Calyculin A
Artikelnummer: Cay19246-10
Calyculin A is a natural, cell-permeable inhibitor of the serine-threonine protein phosphatases (PP) PP1 and PP2A (IC50s = 0.3-0.7 and 0.5-1 nM, respectively). It is without significant effect against PP2B, PP2C, and PP4. Through its effects on PP1 and PP2A, calyculin A has been shown to either promote or inhibit...
| Schlagworte: | (-)-Calyculin A,... |
| Anwendung: | Cell-permeable PP1 / PP2A inhibitor |
| CAS | 101932-71-2 |
| MW: | 1009,2 D |
ab 409,00 €
Calyculin A, Highly Purified
Artikelnummer: C1036-70.100
Calyculin A, a polyene phosphate, was initially isolated from the marine sponge Discodermia calyx. It is a very potent, cell-permeable PP-1 and PP-2 inhibitor (IC50: 2nM and 0.5-1nM respectively, and extremely specific for PP-1 and PP2A classes of protein serine/threonine phosphatase among other acidic, alkaline...
| CAS | 101932-71-2 |
| MW: | 1009.18 D |
1.008,00 €
