Zu "1015474-32-4" wurden 3 Artikel gefunden!
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Avadomide
Artikelnummer: TGM-T3549-25mg
Description: Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity. Target: Molecular Glues, Apoptosis, NF-kappaB, Ligand for E3 Ligase, E1/E2/E3 Enzyme. Smiles: Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O
| Schlagworte: | CC 122 |
| Anwendung: | Antineoplastic, Immunomodulator |
| CAS | 1015474-32-4 |
| MW: | 286.29 D |
ab 30,00 €
CC-122
Artikelnummer: Cay26257-10
CC-122 is a pleiotropic pathway modifier with anticancer activity. It binds to cereblon, a substrate receptor protein of the Cullin 4 RING E3 ubiquitin ligase complex, in U266 multiple myeloma cell extracts and induces recruitment and degradation of the cereblon substrates Aiolos and Ikaros in TMD8, OCI-LY10, and...
| Schlagworte: | Avadomide, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-2,6-piperidinedione |
| Anwendung: | Antineoplastic, immunomodulator |
| CAS | 1015474-32-4 |
| MW: | 286.3 D |
ab 44,00 €
3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2...
Artikelnummer: BPS-82012
3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione has been shown to treat Diffuse large B-cell lymphoma with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon, a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4.
| Anwendung: | Protac(R) reagent |
| CAS | 1015474-32-4 |
| MW: | 286,3 D |
1.343,00 €
