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AM4668
Artikelnummer: Cay43419-1
An FFAR1/GPR40 agonist, induces IP3 production in A9 cells expressing human FFAR1/GPR40 (EC50 = 3.6 nM), induces insulin secretion from pancreatic islets isolated from FFAR1 knock-in mice, reduces blood glucose levels in FFAR1 knock-in mice at 10 mg/kg
| Schlagworte: | betaS-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl]-3-isoxazolepropanoic acid |
| Anwendung: | FFAR1/GPR40 agonist |
| CAS | 1011531-27-3 |
| MW: | 488.48 D |
ab 146,00 €
AM-4668
Artikelnummer: TGM-T14202-100mg
Description: AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively. Target: GPR. Smiles: C(OC1=CC=C([C@H](CC(O)=O)C=2C=CON2)C=C1)C=3SC(=NC3C)C4=CC=C(C(F)(F)F)C=C4. References: Liu JJ, et al. Optimization...
| CAS | 1011531-27-3 |
| MW: | 488.48 D |
ab 1.440,00 €
