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CX-4945
Artikelnummer: Cay16779-10
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2, Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2alpha subunit, conferring selectivity. It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of...
| Schlagworte: | Silmitasertib, 5-[(3-chlorophenyl)amino]-benzo[c]-2,6-naphthyridine-8-carboxylic acid |
| Anwendung: | CK2 inhibitor |
| CAS | 1009820-21-6 |
| MW: | 349.8 D |
ab 84,00 €
![CX-4945 . hydrochloride [Silmitasertib . HCl]](https://www.biomol.com/media/image/85/16/9c/AG-CR1-3629-M001_200x200.png "CX-4945 . hydrochloride [Silmitasertib . HCl]")
CX-4945 . hydrochloride [Silmitasertib . HCl]
Artikelnummer: AG-CR1-3629-M005
Yellow solid. Soluble in DMSO. Insoluble in water. Orally active, potent and selective ATP-competitive inhibitor of the protein kinase CK2 (IC50=1nM), Anticancer compound. Inhibits proliferation in a panel of cancer cell lines that overexpress CK2. Inhibited migration, blocks survival and induces apoptosis in cancer...
| Schlagworte: | Silmitasertib . HCl, 8-Carboxy-N-(3-chlorophenyl)benzo[c][2,6] naphthyridin-5-aminium chloride |
| Anwendung: | Protein kinase CK2 inhibitor |
| CAS | 1009820-21-6 |
| MW: | 386,3 D |
ab 77,00 €
