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AZD 8055
AZD 8055

Artikelnummer: Cay16978-1

AZD 8055 is a potent, selective ATP-competitive inhibitor of mTOR, exhibiting an IC50 value of 0.8 nM. It is ~1,000-fold selective for mTOR over all PI3K isoforms and exhibits no activity against a panel of 260 kinases at concentrations up to 10 µM. AZD 8055 inhibits proliferation of A549 and H838 cells with IC50...
Schlagworte: CCG-168, 5-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-benzenemethanol
Anwendung: mTOR inhibitor
CAS 1009298-09-2
MW: 465.5 D
ab 60,00 €
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AZD-8055
AZD-8055

Artikelnummer: SYN-1166-M100

Soluble in DMSO or ethanol. AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC(50) of 0.8nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family. Target: mTOR , Kinase Group:...
Schlagworte: AZD8055, CCG168
Anwendung: mTOR inhibitor
CAS 1009298-09-2
MW: 465,5 D
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AZD-8055
AZD-8055

Artikelnummer: LKT-A9914.5

mTOR inhibitor.
Schlagworte: AZD-8055
Anwendung: mTOR inhibitor
CAS 1009298-09-2
MW: 465.55 D
ab 100,00 €
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AZD8055, Free Base (CCG-168, CAS 1009298-09-2), >99%
AZD8055, Free Base (CCG-168, CAS 1009298-09-2), >99%

Artikelnummer: LC-A-2345_100mg

Soluble in DMSO at 50 mg/mL, soluble in ethanol at 20 mg/mL with warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 50-100 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Schlagworte: CCG-168, 5-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-benzenemethanol
Anwendung: mTOR inhibitor
CAS 1009298-09-2
MW: 465,54 D
ab 80,00 €
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