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Golgicide A
Artikelnummer: Cay18430-10
ADP-ribosylation factor 1 (Arf1), when activated by guanine nucleotide exchange factors (ArfGEFs), plays a key role in regulating secretory traffic and membrane transport within the Golgi of eukaryotic cells. Golgicide A is a reversible inhibitor of the brefeldin A (Cay-11861)-resistant, cis-Golgi ArfGEF, GBF1 (IC50...
| Schlagworte: | GCA, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline |
| Anwendung: | Reversible GBF1 inhibitor |
| CAS | 1005036-73-6 |
| MW: | 284.3 D |
ab 126,00 €
(Rac)-Golgicide A
Artikelnummer: TGM-T38399-5mg
Description: (Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A, used in the synthesis of Golgicide A. Target: Virus Protease. Smiles: FC=1C=C(F)C=2NC(C=3C=NC=CC3)C4CC=CC4C2C1. References: Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009...
| Schlagworte: | (Rac)-GCA |
| Anwendung: | Reversible GBF1 inhibitor |
| CAS | 1005036-73-6 |
| MW: | 284.3 D |
918,00 €
