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INH6
Artikelnummer: TGM-T6180-10mg
Description: INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment. Target: Apoptosis, Microtubule Associated. Smiles: Cc1cc(C)c(-c2csc(NC(=O)c3ccccc3)n2)c(C)c1. References: Qiu XL, et al. J Med Chem. 2009, 52(6), 1757-1767.
| Anwendung: | NDC80 inhibitor |
| CAS | 1001753-24-7 |
| MW: | 322.42 D |
ab 42,00 €
INH6
Artikelnummer: Cay21772-1
INH6 is an inhibitor of the oncogene high expression in cancer 1 (Hec1) and its regulator, the serine-threonine kinase Nek2, which together regulate mitotic spindle formation. It inhibits proliferation in human breast, cervical, and leukemia cell lines with IC50 values of 1.7 and 2.1, 2.4, and 2.5 µM, respectively,...
| Schlagworte: | N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-benzamide |
| Anwendung: | NDC80 inhibitor |
| CAS | 1001753-24-7 |
| MW: | 322.4 D |
ab 47,00 €
