Zu "100079-26-3" wurden 2 Artikel gefunden!
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THPN
Artikelnummer: Cay45944-1
THPN is an inducer of autophagy and a derivative of gallic acid (Cay-11846). It binds to the ligand-binding domain (LBD) of Nur77 (Kd = 0.27 µM), which increases NIP3L-facilitated translocation of Nur77 to the mitochondria and induces autophagy in A375 melanoma cells. THPN reduces viability of L1210 and CEM leukemia...
| Schlagworte: | 1-(3,4,5-trihydroxyphenyl)-1-nonanone |
| Anwendung: | Autophagy inducer |
| CAS | 100079-26-3 |
| MW: | 266.34 D |
ab 42,00 €
THPN
Artikelnummer: TGM-T24880-100mg
Description: THPN is a Nur77 agonist. It also induces autophagy in melanoma cell lines. Target: Others. Smiles: C(CCCCCCCC)(=O)C1=CC(O)=C(O)C(O)=C1. References: Wang et al (2014) Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat.Chem.Biol. 10 133 PMID: 24316735
| CAS | 100079-26-3 |
| MW: | 266.33 D |
ab 1.440,00 €
