Zu "1000025-07-9" wurden 2 Artikel gefunden!
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Vadadustat
Artikelnummer: Cay15295-5
Vadadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) and HIF-PH3 (IC50s = 1.1 and 0.39 micromolar, respectively). It stabilizes HIF-1alpha in mouse hepatocyte nuclear extracts. Vadadustat (50 and 100 mg/kg) increases erythropoietin levels in mouse serum.Formal Name:...
| Schlagworte: | AKB6548, PG-1016548, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-glycine |
| Anwendung: | PHD2 / PHD3 inhibitor |
| CAS | 1000025-07-9 |
| MW: | 306.7 D |
ab 93,00 €
Vadadustat
Artikelnummer: TGM-T4651-25mg
Description: Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia. Target: HIF, HIF/HIF Prolyl-Hydroxylase. Smiles: OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(Cl)c1. References: Pergola PE, et al. Vadadustat, a novel oral HIF...
| Schlagworte: | PG-1016548, AKB-6548 |
| Anwendung: | Targets hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] (EGLN, HPH) |
| CAS | 1000025-07-9 |
| MW: | 306.7 D |
ab 40,00 €
