Zu "968" wurden 1547 Artikel gefunden!
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Riociguat
Artikelnummer: TGM-T6968-5mg
Description: Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension. Target: Guanylate cyclase. Smiles: COC(=O)N(C)c1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncccc12. References: Reiss C, et al. Br J Pharmacol....
| Schlagworte: | BAY 632521 |
| Anwendung: | Targets guanylate cyclase soluble subunit alpha [EC:4.6.1.2] (GUCY1A) |
| CAS | 625115-55-1 |
| MW: | 422.42 D |
ab 35,00 €
Zotepine
Artikelnummer: TGM-T19680-10mg
Description: Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, alpha1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. This second-generation antipsychotic is primarily used to treat schizophrenia, and clinical trials...
| Anwendung: | Targets dopamine receptor D2 (DRD2) |
| CAS | 26615-21-4 |
| MW: | 331.86 D |
ab 30,00 €
Dansylcadaverine
Artikelnummer: TGM-T18968-50mg
Description: Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe. Target: Autophagy, Others. Smiles: CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN. References: Huff T, et al. Thymosin beta(4) serves as a glutaminyl substrate of transglutaminase. Labeling with fluorescentdansylcadaverine does not abolish...
| Schlagworte: | Monodansyl cadaverine |
| CAS | 10121-91-2 |
| MW: | 335.46 D |
ab 29,00 €
Anti-CD90 (Biotin), clone G7
Artikelnummer: ARG20968.100
Protein function: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [The UniProt Consortium]
| Schlagworte: | Anti-CD90, Anti-Thy1, Anti-Thy-1, Anti-Thy-1 antigen, Anti-Thy-1 membrane glycoprotein |
| Anwendung: | FC, IHC (paraffin), Cell-Act |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
586,00 €
Anti-MUC1 / EMA, clone GP1.4
Artikelnummer: ARG55968.50
Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
| Schlagworte: | Anti-PUM, Anti-MUC1 |
| Anwendung: | FC, ICC, IF, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-FABP4, clone 3F4
Artikelnummer: ARG56968.50
Protein function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. [The UniProt Consortium]
| Schlagworte: | Anti-ALBP, Anti-AFABP, Anti-FABP4, Anti-A-FABP, Anti-Fatty acid-binding protein 4, Anti-Adipocyte lipid-binding protein,... |
| Anwendung: | WB, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
518,00 €
Anti-Ezrin / villin 2
Artikelnummer: ARG63968.100
Protein function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis. [The UniProt Consortium]
| Schlagworte: | Anti-p81, Anti-EZR, Anti-VIL2, Anti-Ezrin, Anti-Villin-2, Anti-Cytovillin |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
ab 598,00 €
Anti-HMOX2, Internal
Artikelnummer: ARG64968.100
Protein function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and...
| Schlagworte: | Anti-HO2, Anti-HO-2, Anti-HMOX2, EC=1.14.99.3, Anti-Heme oxygenase 2 |
| Anwendung: | ELISA, WB, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
COVID-19 Forschung
Rat ACE2 ELISA Kit
Artikelnummer: ARG80968.96
Protein function: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. [The UniProt Consortium]
| Schlagworte: | Anti-Ace2, EC=3.4.17.23 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
2.147,00 €
Anti-Hakai
Artikelnummer: A302-968A
Protein function: Promotes ubiquitination of several tyrosine- phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. [The UniProt Consortium]
| Schlagworte: | Anti-CBLL1, Anti-HAKAI, EC=2.3.2.27, Anti-c-Cbl-like protein 1, Anti-RING finger protein 188, Anti-E3 ubiquitin-protein... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SLBP
Artikelnummer: A303-968A
Protein function: RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the...
| Schlagworte: | Anti-HBP, Anti-SLBP, Anti-Histone stem-loop-binding protein, Anti-Histone RNA hairpin-binding protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Fenbendazole
Artikelnummer: Cay19687-10
Fenbendazole is a benzimidazole anthelmintic. It is active against Giardia in vitro (IC50 = 0.3 µM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. Fenbendazole also activates HIF-1alpha and prevents oxidative stress-induced death in primary...
| Schlagworte: | Methyl 5-(phenylthio)-2-benzimidazolecarbamate, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Anwendung: | Anthelmintic, tubulin binding |
| CAS | 43210-67-9 |
| MW: | 299.3 D |
ab 97,00 €