Cellular Senescence Fluorometric Assay Kit

The senescence-associated beta-galactosidase (SA-beta-gal) is a key biomarker of cellular senescence. Studies have shown that the activity of this enzyme significantly increases in senescent cells and is related to abnormal lysosomal function. It is commonly used to detect the state of cellular senescence and study the mechanism of aging. This kit can detect the activity of SA-beta-gal in cells through a simple fluorescence method. The probe can enter the cell through the cell membrane, and SA-beta-gal hydrolyzes the probe to emit fluorescence. The fluorescence intensity can be detected using a flow cytometer to determine the activity of SA-beta-gal.