ICG Maleimide

ICG Maleimide
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABD-187 1 mg -

3 - 8 Werktage*

346,00 €
 
Ex: 780 nm. Em: 800 nm. Soluble in: DMSO. Indocyanine green (ICG) is a cyanine dye used in... mehr
Produktinformationen "ICG Maleimide"
Ex: 780 nm. Em: 800 nm. Soluble in: DMSO. Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. It has a peak spectral absorption close to 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. ICG binds tightly to plasma proteins and becomes confined to the vascular system. ICG has a half-life of 150 to 180 seconds and is removed from circulation exclusively by the liver to bile juice. A recent study indicated ICG targets atheromas within 20 min of injection and provides sufficient signal enhancement for in vivo detection of lipid-rich, inflamed, coronary-sized plaques in atherosclerotic rabbits. Ex vivo fluorescence reflectance imaging showed high plaque target-to-background ratios in atheroma-bearing rabbits injected with ICG compared to atheroma-bearing rabbits injected with saline. This thiol-reactive ICG derivative is used to make ICG bioconjugates with antibodies and other biological molecules.
Hersteller: AAT Bioquest
Hersteller-Nr: 187

Eigenschaften

Anwendung: Conjugation
MW: 853,09 D
Format: Desiccated

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (protect from light)
Versand: -20°C (International: °C)
Signalwort: Warning
P-Sätze: P304, P312
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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