Thyrotropin receptor (Tshr), partial, mouse, recombinant

Organism: Mus musculus (Mouse). Source: Baculovirus. Expression Region: 22-413aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: KECASPPCEC HQEDDFRVTC KELHRIPSLP PSTQTLKLIE THLKTIPSLA FSSLPNISRI YLSIDATLQR LEPHSFYNLS KMTHIEIRNT RSLTYIDPDA LTELPLLKFL GIFNTGLRIF PDLTKIYSTD IFFILEITDN PYMTSVPENA FQGLCNETLT LKLYNNGFTS VQGHAFNGTK LDAVYLNKNK YLTAIDNDAF GGVYSGPTLL DVSSTSVTAL PSKGLEHLKE LIAKDTWTLK KLPLSLSFLH LTRADLSYPS HCCAFKNQKK IRGILESLMC NESSIRNLRQ RKSVNILRGP IYQEYEEDPG DNSVGYKQNS KFQESPSNSH YYVFFEEQED EVVGFGQELK NPQEETLQAF ESHYDYTVCG DNEDMVCTPK SDEFNPCEDI MG. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Receptor for the thyroid-stimulating hormone or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Reference: "Effect of primary congenital hypothyroidism upon expression of genes mediating murine brain glucose uptake." Khan J.Y., Rajakumar R.A., Devaskar U.P., Weissfeld L.A., Devaskar S.U. Pediatr. Res. 45:718-725(1999). Function: nan