Synapsin-2 (Syn2), partial, rat, recombinant

Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 88-422aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: LSQAVKQTAA SAGLVDAPAP SAASRKAKVL LVVDEPHTDW AKCFRGKKIL GDYDIKVEQA EFSELNLVAH ADGTYAVDMQ VLRNGTKVVR SFRPDFVLIR QHAFGMAENE DFRHLVIGMQ YAGLPSINSL ESIYNFCDKP WVFAQMVAIF KTLGGEKFPL IEQTYYPNHR EMLTLPTFPV VVKIGHAHSG MGKVKVENHY DFQDIASVVA LTQTYATAEP FIDAKYDIRV QKIGNNYKAY MRTSISGNWK TNTGSAMLEQ IAMSDRYKLW VDACSEMFGG LDICAVKAVH GKDGKDYIFE VMDCSMPLIG EHQVEDRQLI TDLVISKMNQ LLSRT. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons. Reference: "A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini." Lam P.P., Hyvaerinen K., Kauppi M., Cosen-Binker L., Laitinen S., Keraenen S., Gaisano H.Y., Olkkonen V.M. Mol. Biol. Cell 18:2473-2480(2007). Function: nan