Recombinant Human TMEM182 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Leu31. End Site: Glu100. Coverage: 0.39. Isoelectric Point: 5.5. Core Sequence: LLATEVGRCS GEKNIENVTF HHEGFFWRCW FNGIVEENDS NIWKFWYTNQ PPSKNCTHAY LSPYPFMRGE. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 94%, Pig - 94%, Cynomolgus monkey - 96%, Protein Function: Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (By similarity). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (By similarity) [The Uniprot Consortium]