Recombinant Human SRI Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Thr31. End Site: Thr170. Coverage: 0.75. Isoelectric Point: 5.5. Core Sequence: TQDPLYGYFA AVAGQDGQID ADELQRCLTQ SGIAGGYKPF NLETCRLMVS MLDRDMSGTM GFNEFKELWA VLNGWRQHFI SFDTDRSGTV DPQELQKALT TMGFRLSPQA VNSIAKRYST NGKITFDDYI ACCVKLRALT. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 97%, Rat - 37%, Pig - 99%, Cynomolgus monkey - 99%, Protein Function: Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels [The Uniprot Consortium]