Recombinant Human Mast Cell Chymase Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Ile22. End Site: Asn247. Coverage: 1. Isoelectric Point: 8. Core Sequence: IIGGTECKPH SRPYMAYLEI VTSNGPSKFC GGFLIRRNFV LTAAHCAGRS ITVTLGAHNI TEEEDTWQKL EVIKQFRHPK YNTSTLHHDI MLLKLKEKAS LTLAVGTLPF PSQFNFVPPG RMCRVAGWGR TGVLKPGSDT LQEVKLRLMD PQACSHFRDF DHNLQLCVGN PRKTKSAFKG DSGGPLLCAG VAQGIVSYGR SDAKPPAVFT RISHYRPWIN QILQAN. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 75%, Rat - 74%, Pig - 61%, Cynomolgus monkey - 98%, Protein Function: Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion [The Uniprot Consortium]