Recombinant Human HSD3B2 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Gly11. End Site: Gly140. Coverage: 0.38. Isoelectric Point: 5. Core Sequence: GGLLGQRIVR LLVEEKELKE IRALDKAFRP ELREEFSKLQ NRTKLTVLEG DILDEPFLKR ACQDVSVVIH TACIIDVFGV THRESIMNVN VKGTQLLLEA CVQASVPVFI YTSSIEVAGP NSYKEIIQNG. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 72%, Rat - 71%, Pig - 76%, Cynomolgus monkey - 96%, Protein Function: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids [The Uniprot Consortium]