Recombinant Human EYS Protein

Tag: C-His. Modification: unmodified. Start Site: Gln171. End Site: Glu330. Coverage: 0.05. Isoelectric Point: 7. Core Sequence: QQFCQESLSS EFCSGHGKCL SEAWSKTYSC HCQPPFSGKY CQELDACSFK PCKNNGSCIN KRENWDEQAY ECVCHPPFTG KNCSEIIGQC QPHVCFHGNC SNITSNSFIC ECDEQFSGPF CEVSAKPCVS LLFWKRGICP NSSSAYTYEC PKGSSSQNGE. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 36%, Rat - 42%, Pig - 71%, Cynomolgus monkey - 96%, Protein Function: Required to maintain the integrity of photoreceptor cells (PubMed:18836446). Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone (By similarity) [The Uniprot Consortium]