Recombinant Human COLGALT1 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Leu301. End Site: Trp420. Coverage: 0.22. Isoelectric Point: 6. Core Sequence: LQDEAESFMH VQLEVMVKHP PAEPSRFISA PTKTPDKMGF DEVFMINLRR RQDRRERMLR ALQAQEIECR LVEAVDGKAM NTSQVEALGI QMLPGYRDPY HGRPLTKGEL GCFLSHYNIW. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 90%, Rat - 54%, Pig - 93%, Cynomolgus monkey - 67%, Protein Function: Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen (PubMed:19075007, PubMed:22216269, PubMed:27402836). By acting on collagen glycosylation, facilitates the formation of collagen triple helix (PubMed:27402836). Also involved in the biosynthesis of collagen type IV (PubMed:30412317) [The Uniprot Consortium]