Recombinant Human CDKAL1 Protein

Tag: C-His. Modification: unmodified. Start Site: Asp21. End Site: Gly190. Coverage: 0.29. Isoelectric Point: 9. Core Sequence: DSKPQDRHFV RKDVVPKVRR RNTQKYLQEE ENSPPSDSTI PGIQKIWIRT WGCSHNNSDG EYMAGQLAAY GYKITENASD ADLWLLNSCT VKNPAEDHFR NSIKKAQEEN KKIVLAGCVP QAQPRQDYLK GLSIIGVQQI DRVVEVVEET IKGHSVRLLG QKKDNGRRLG. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 95%, Rat - 29%, Pig - 97%, Cynomolgus monkey - 99%, Protein Function: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine [The Uniprot Consortium]