Recombinant Human Bcl2 A1 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Arg11. End Site: Pro150. Coverage: 0.86. Isoelectric Point: 5. Core Sequence: RLAQDYLQCV LQIPQPGSGP SKTSRVLQNV AFSVQKEVEK NLKSCLDNVN VVSVDTARTL FNQVMEKEFE DGIINWGRIV TIFAFEGILI KKLLRQQIAP DVDTYKEISY FVAEFIMNNT GEWIRQNGGW ENGFVKKFEP. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 72%, Rat - 37%, Pig - 87%, Cynomolgus monkey - 96%, Protein Function: Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity) [The Uniprot Consortium]