Recombinant Human ALAD Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Tyr11. End Site: Asp270. Coverage: 0.82. Isoelectric Point: 6. Core Sequence: YFHPLLRAWQ TATTTLNASN LIYPIFVTDV PDDIQPITSL PGVARYGVKR LEEMLRPLVE EGLRCVLIFG VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD VCLCPYTSHG HCGLLSENGA FRAEESRQRL AEVALAYAKA GCQVVAPSDM MDGRVEAIKE ALMAHGLGNR VSVMSYSAKF ASCFYGPFRD AAKSSPAFGD RRCYQLPPGA RGLALRAVDR DVREGADMLM VKPGMPYLDI VREVKDKHPD. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 89%, Rat - 88%, Pig - 92%, Cynomolgus monkey - 98%, Protein Function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen [The Uniprot Consortium]