RBP4, Recombinant, Human (Retinol Binding Protein 4)

Retinol binding protein 4 (RBP4, RBP) is a 21kD secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function. Sequence: Human RBP4 (aa 19-201) is fused at the N-terminus to a FLAG(R)-tag. Storage and Stability: Short-term Storage: +4°C, Long-term Storage: -20°C, Working aliquots are stable for up to 3 months when stored at -20°C.