Protein Disulfide-Isomerase-Like Protein of the Testis/PDILT Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Protein Disulfide-Isomerase-Like Protein of the Testis is produced by our Mammalian expression system and the target gene encoding Ser21-Leu584 is expressed with a 6His tag at the C-terminus. Sequence: Ser21-Leu584. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 92 kDa. Protein function: Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid signal sequence and a 564 amino acid mature chain. PDILT contains 1 thioredoxin domain lacks the conserved redox-active Cys at position 417 which is replaced by a Ser residue, suggesting that it lacks thioredoxin activity. PDILT is an enzyme in the endoplasmic reticulum in eukaryotes. It is not a disulfide-linked homodimer. The PDILT protein can interacts with ERO1L and CLGN. PDILT probable redox-inactive chaperone involved in spermatogenesis. Protein function: Probable redox-inactive chaperone involved in spermatogenesis. [The UniProt Consortium]