Pertussis Toxin from Bordetella pertussis (lyophilized, salt free)

Pertussis toxin was first isolated from B. pertussis and is used to study G protein-coupled receptor signaling in cells and experimental autoimmune encephalomyelitis (EAE) in animals. Pertussis toxin catalyzes the transfer of the ADP-ribose moiety of NAD to the alpha subunits of heterotrimeric Gi/o proteins, resulting in the receptors being uncoupled from Gi/o proteins. Pertussis toxin is also used as an adjuvant, given with specific antigens, to immunize animals and induce EAE, an animal model of multiple sclerosis.Purity: >95% (estimated by SDS-PAGE). Formulation: (Request formulation change), 50 µg of lyophilized pertussis toxin. Solubility: Water: soluble.