PDZD7_1 PDZ Domain

The protein is provided in 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2 and 25% (v/v) glycerol, at a 0.5 mg/mL concentration.Sequence: DIIHSVRVEK SPAGRLGFSV RGGSEHGLGI FVSKVEEGSS AERAGLCVGD KITEVNGLSL ESTTMGSAVK VLTSSSRLHM MVRRMGRVP. Components: PDZD7_1 PDZ Domain. Shipping Conditions: Room Temperature. Storage Conditions: -30°C to -15°C. Application: Drug Discovery. Optimal pH: 7. Optimal Temperature: 36.5 °C. Features: Optimum temperature: 36.5 °C, pH: 7.0, Protein concentration: 0.5 mg/mL, Recombinant protein purified from Escherichia coli. Product Category: PDZ Domains. Molecular Weight: 12,34 KDa. Protein function: In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1. [The UniProt Consortium]