Netrin-G1/NTNG1 Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Netrin-G1 is produced by our Mammalian expression system and the target gene encoding His29-Ser409 is expressed with a 6His tag at the C-terminus. Sequence: His29-Ser409. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 51 kDa. Protein function: Netrin-G1 (NTNG1) is a member of a conserved family of proteins that act as axon guidance cues during vertebrate nervous system development. Netrin-G1 contains one laminin EGF-like domain and one laminin N-terminal domain, Netrin-G1 is highly expressed in the thalamus, lowly in other tissue. Netrin-G1 localizes to the cell membrane. Netrin-G1 interacts with NGL1 and is glycosylated in the N-terminal. In addition, Netrin-G1 can promotesneurite outgrowth of both axons and dendrites. Protein function: Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites. [The UniProt Consortium]