Mouse MUC18/CD146 Protein

Recombinant Mouse MUC18/CD146 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val24-Val563. METCAM/MUC18 is an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family. It can carry out common functions of CAMs which is to perform intercellular interactions and interaction of cell with extracellular matrix in tumor microenvironment, to interact with various signaling pathways and to regulate general behaviors of cells.The above positive correlation is fortuitous, actually METCAM/MUC18 acts as a tumor and metastasis suppressor for the ovarian carcinoma cells.