Mouse GITR, recombinant (C-Fc-6His)

Recombinant Mouse Glucocorticoid Induced TNF Receptor Family Related Gene is produced by our Mammalian expression system and the target gene encoding Ser22-His153 is expressed with a human IgG1 Fc, 6His tag at the C-terminus. Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]