Mouse CLEC-1 Protein

Recombinant Mouse CLEC-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln73-Gln269. C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1beta production in response to A. fumigatus keratitis.