Mouse CD21 Protein

Recombinant Mouse CD21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile12-Trp963. A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes.