Macaque CD79B/B29 (C-6His) (recombinant rhesus)

Protein Construction: Recombinant Rhesus macaque CD79B is produced by our Mammalian expression system and the target gene encoding Ala30-Asp161 is expressed with a 6His tag at the C-terminus. Sequence: Ala30-Asp161. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 20-30 kDa. Protein function: CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.