La-related protein 6 (LARP6), human, recombinant

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-491aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AQSGGEARPG PKTAVQIRVA IQEAEDVDEL EDEEEGAETR GAGDPARYLS PGWGSASEEE PSRGHSGTTA SGGENEREDL EQEWKPPDEE LIKKLVDQIE FYFSDENLEK DAFLLKHVRR NKLGYVSVKL LTSFKKVKHL TRDWRTTAHA LKYSVVLELN EDHRKVRRTT PVPLFPNENL PSKMLLVYDL YLSPKLWALA TPQKNGRVQE KVMEHLLKLF GTFGVISSVR ILKPGRELPP DIRRISSRYS QVGTQECAIV EFEEVEAAIK AHEFMITESQ GKENMKAVLI GMKPPKKKPA KDKNHDEEPT ASIHLNKSLN KRVEELQYMG DESSANSSSD PESNPTSPMA GRRHAATNKL SPSGHQNLFL SPNASPCTSP WSSPLAQRKG VSRKSPLAEE GRLNCSTSPE IFRKCMDYSS DSSVTPSGSP WVRRRRQAEM GTQEKSPGTS PLLSRKMQTA DGLPVGVLRL PRGPDNTRGF HGHERSRACV. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. Reference: "Acheron, a novel member of the Lupus antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta." Valavanis C., Wang Z., Sun D., Vaine M., Schwartz L.M. Gene 393:101-109(2007). Function: nan