IRX3 PrEST Antigen

PrEST Antigen IRX3, Gene description: iroquois homeobox 3, Alternative Gene Names: IRX-1, Antigen sequence: GEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPI, Storage: Upon delivery store at -20°C. Avoid repeated freeze/thaw cycles. Protein function: Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism. [The UniProt Consortium] Mouse gene identity: 84% Rat gene identity: 84%