IgG2C Protein, Mouse, Recombinant

Description: Mouse IgG2c is a subclass of mouse antibody IgG, it can bind FcgammaRIV with high affinity and the Fc loop residues of mouse IgG2c promote greater receptor-binding affinity than mouse IgG2b or human IgG1. References: Falconer DJ, Barb AW. Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgGPLoS One. 2018 Feb 6,13(2):e0192123. doi: 10.1371/journal.pone.0192123. Erratum in: PLoS One. 2018 Apr 24,13(4):e0196609. PMID: 29408873, PMCID: PMC5800599. (2) Nazeri S, Zakeri S, Mehrizi AA, Sardari S, Djadid ND. Measuring of IgG2c isotype instead of IgG2a in immunized C57BL/6 mice with Plasmodium vivax TRAP as a subunit vaccine candidate in order to correct interpretation of Th1 versus Th2 immune response. Exp Parasitol. 2020 Sep,216:107944. doi: 10.1016/j.exppara.2020.107944. Epub 2020 Jun 30. PMID: 32619431.