Human TMIGD2, recombinant (C-6His)

Recombinant Human Transmembrane And immunoglobulin Domain-containing Protein 2 is produced by our Mammalian expression system and the target gene encoding Leu23-Gly150 is expressed with a 6His tag at the C-terminus. Protein function: Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [The UniProt Consortium]