Human PAQRB-Strep full length protein-synthetic nanodisc

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]. Human PAQRB-Strep full length protein-synthetic nanodisc. Protein function: Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion. [The UniProt Consortium]