Human IL-18RAcP, recombinant (C-Fc-6His)

Recombinant Human Interleukin-18 receptor accessory protein is produced by our Mammalian expression system and the target gene encoding Phe20-Arg356 is expressed with a human IgG1 Fc, 6His tag at the C-terminus. Protein function: Within the IL18 receptor complex, does not mediate IL18- binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). [The UniProt Consortium]