Human GITR, recombinant (C-mFc)

Recombinant human Glucocorticoid Induced TNF Receptor Family Related Gene is produced by our Mammalian expression system and the target gene encoding Gln26-Glu161(Thr45Ala) is expressed with a mouse IgG1 Fc tag at the C-terminus. Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]