Human CDK2AP2, recombinant (C-6His)

Recombinant Human Cyclin-Dependent Kinase 2-Associated Protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Thr126 is expressed with a 6His tag at the C-terminus. Protein function: Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation, represses CDK2 activation by inhibiting its interaction with cyclin E and A (PubMed:23781148). [The UniProt Consortium]