Human CD13/ANPEP Protein

Recombinant Human CD13/ANPEP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys69-Lys967. CD13/aminopeptidase N is a widely expressed ectoenzyme with multiple functions. As an enzyme, CD13 regulates activities of numerous cytokines by cleaving their N-terminals and is involved in Ag processing by trimming the peptides bound to MHC class II. Independent of its enzymatic activity, cell membrane CD13 functions by cross-linking-induced signal transduction, regulation of receptor recycling, enhancement of FcgammaR-mediated phagocytosis, and acting as a receptor for cytokines.