Human BCAM Protein

Recombinant Human BCAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Ala547. Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-alpha5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.