Human ALDH1A3, recombinant (N-6His)

Recombinant Human Aldehyde Dehydrogenase Family 1 Member A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus. Protein function: NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:27759097). Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (PubMed:27759097). Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions, retinoic acid is required for normal embryonic development of the eye and the nasal region. [The UniProt Consortium]