Histone H3-H4 Tetramer H3k27cMe3

Human recombinant histone tetramer consisting of 2 molecules each of histones H3 (a.a. 2-136(end)) and H4 (a.a. 2-103(end)), expressed in an E. coli expression system. Histone H3 has K27C, C97A, and C111A mutations and was alkylated to produce the lysine analog, trimethyl aminoethylcysteine. GenBank Accession Nos. NM_003532, and NM_003548, respectively. Each histone protein has an N-terminal Histag. Global MW = 57 kDa.