FasL, Soluble, Recombinant, Human (APO-1L, CD95L, CD178, TNFSF6, Fas Ligand)

FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development. Biological Activity: Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1ug/ml TNF Ligands Enhancer. In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations. Sequence: The extracellular domain of human FasL (aa 103-281) is fused at the N-terminus to a FLAG(R)-tag. Endotoxin: <0.05EU/ug (LAL test, Lonza), Storage and Stability: Short-term Storage: +4°C, Long-term Storage: -20°C, Stable for at least 6 months after receipt when stored at -20°C.