DNER (extracellular domain):Fc, Recombinant, Human (BET, UNQ262/PRO299, Delta and Notch-like Epiderm

DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis. Biological Activity: Inhibits adipogenesis of 3T3L-1 cells. Sequence: Signal peptide and extracellular domain of human DNER (aa 1-637) are fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4°C, Long-term Storage: -20°C, Working aliquots are stable for up to 3 months when stored at -20°C.