DNAJC13 (human), recombinant protein

Protein function: Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane, via association with WASHC2 may link the WASH complex to the retromer SNX-BAR subcomplex (PubMed:24643499). [The UniProt Consortium]